Latest Updates

Substance Use Disorders

F Gerard Moeller, MD

    Depressive Disorders: Update on Diagnosis, Etiology, and Treatment

    Isabelle E. Bauer, PhD, Marsal Sanches, MD, PhD, Jair C. Soares, MD, Antonio L Teixeira, MD, PhD
      • 2017 Japan Society for Equilibrium Research guideline on classification, diagnostic criteria, and management of benign paroxysmal positional vertigo
      • Latest American Physical Therapy Association guideline on vestibular rehabilitation for peripheral vestibular hypofunction

    Primary and Preventive Care of Women

    Janet B. Henrich, MD

      Treatment of Arterial Ulcers

      Cameron Akbari, MD, MBA, FACS, Karen K Evans, MD, David E Janhofer, BS, Vahram Ornekian, MD, MS, RPVI
        • Patients with peripheral arterial disease require antiplatelet and statin medication for prevention of cardiovascular events
        • Treatment of ulcer infection should precede any attempt at revascularization of the foot
        • TASC A-B lesions are amenable to endovascular intervention; TASC C-D lesions require surgery
        • After revascularization, toe/partial foot amputations and/or local flaps can be performed for wound healing
        • Nonambulatory patients may benefit from primary amputation instead of attempts at limb salvage

      Burn Resuscitation

      Theresa L. Chin, MD, MPH, Nicole Gibran, MD, FACS, Samuel P Mandell, MD, MPH
        • Accurate estimation of burn size (percent total body surface area; % TBSA) is critical for appropriate fluid resuscitation volume.
        • Most adult patients with burn size less than 20%TBSA and pediatric patients with burn size less than 15% TBSA typically do not require intravenous resuscitation.
        • The mainstay of burn resuscitation is based on continuous fluid administration, not on fluid boluses.
        • Judicious intravenous fluid use reduces fluid creep and resuscitation-related complications.
        • Therapies such as renal replacement therapy (continuous venovenous hemodialysis, dialysis), plasmapheresis, or colloid administration may facilitate resuscitation in patients who are refractory to crystalloids.

      Uroneurology

      Jalesh N. Panicker, MBBS, MD, DM, MRCP, Jai H Seth, MBBS, MRCS, BSc, MSc

        The Future of Transplant Biology and Surgery

        Anthony Atala, MD, Marc Colaco, MD, MBA
          • Although allotransplant remains the gold standard for organ transplant, bioengineering offers future possibilities to alleviate the donor organ shortage.
          • New applications of bioengineering are regularly being seen in clinical investigation and are nearing widespread clinical application.
          • New technologies such as three-dimensional printing are becoming increasingly cost-effective and allow for both experimentation and eventual clinical production.

        Contemporary Evidence-Based Approach to the Couple Experiencing Recurrent Pregnancy Loss: Standardizing Terminology, Testing, and Treatment

        Channing Burks, MD, Danny J Schust, MD, Mary D Stephenson, MD, MSc
          • Recurrent pregnancy loss (RPL) should be defined as two or more pregnancy losses at any gestational age, not necessarily consecutive.
          • At second pregnancy loss, miscarriage chromosome testing is essential to determining whether an RPL evaluation is indicated. Fifty to 70% of pregnancy losses of less than 10 weeks gestational age are due to a random numeric chromosome errors (“explained miscarriages”).
          • If a miscarriage is found to be euploid (46,XX of pregnancy origin, 46,XY, or a balanced structural chromosome rearrangement), it is termed an “unexplained” miscarriage, and an RPL evaluation is indicated.
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